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1

Human Studies with the Chelating Agents, DMPS and DMSA

Vasken Aposhian, H., Maiorino, Richard M., Rivera, Mario, Bruce, David C., Dart, Richard C., Hurlbut, Katherine M., Levine, Deborah J., Zheng, Wei, Fernando, Quintus, Carter, Dean, Aposhian, Mary M.

Journal:

Clinical Toxicology (Informa Healthcare)

Année:

1992

Langue:

english

Fichier:

PDF, 1.05 MB

english, 1992

2

Vitamin C, Glutathione, Or Lipoic Acid Did Not Decrease Brain Or Kidney Mercury In Rats Exposed To Mercury Vapor†

Vasken Aposhian, H., Morgan, Daniel L., Sam Queen, H. L., Maiorino, Richard M., Aposhian, Mary M.

Journal:

Clinical Toxicology (Informa Healthcare)

Année:

2003

Langue:

english

Fichier:

PDF, 164 KB

english, 2003

3

Sodium 2,3-dimercapto-1-propanesulfonate (DMPS) treatment does not redistribute lead or mercury to the brain of rats

Mary M. Aposhian, Richard M. Maiorino, Zhaofa Xu, H.Vasken Aposhian

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 686 KB

english, 1996

4

A review of the enzymology of arsenic metabolism and a new potential role of hydrogen peroxide in the detoxication of the trivalent arsenic species

H Vasken Aposhian, Robert A Zakharyan, Mihaela D Avram, Adriana Sampayo-Reyes, Michael L Wollenberg

Journal:

Toxicology and Applied Pharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 669 KB

english, 2004

5

Arsenic Exposure and Health Effects III || How is Inorganic Arsenic Detoxified?

Aposhian, H. Vasken

Année:

1999

Langue:

english

Fichier:

PDF, 564 KB

english, 1999

6

ENZYMATIC METHYLATION OF ARSENIC SPECIES AND OTHER NEW APPROACHES TO ARSENIC TOXICITY

Aposhian, H. Vasken

Journal:

Annual Review of Pharmacology

Année:

1997

Langue:

english

Fichier:

PDF, 193 KB

english, 1997

7

An efficient synthesis of sodium dimethylarsinate-14C

Bhumasamudram Jagadish, H. Vasken Aposhian, Eugene A. Mash

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Année:

2003

Langue:

english

Fichier:

PDF, 72 KB

english, 2003

8

Determination and metabolism of dithiol-chelating agents: Electrolytic and chemical reduction of oxidized dithiols in urine

Richard M. Maiorino, Timothy J. Barry, H.Vasken Aposhian

Journal:

Analytical Biochemistry

Année:

1987

Langue:

english

Fichier:

PDF, 760 KB

english, 1987

9

Lead chelates of meso- and racemic-dimercaptosuccinic acid

Mario Rivera, Quintus Fernando, H.Vasken Aposhian

Journal:

Journal of Inorganic Biochemistry

Année:

1989

Langue:

english

Fichier:

PDF, 978 KB

english, 1989

10

Neurotoxicity of metals: the new challenges. Introductory remarks

H.Vasken Aposhian, Symposium Chair

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 155 KB

english, 1995

11

Arsenic binding proteins of mammalian systems: I. Isolation of three arsenite-binding proteins of rabbit liver

Gregory M. Bogdan, Adriana Sampayo-Reyes, H. Vasken Aposhian

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 1.34 MB

english, 1994

12

Mobilization of heavy metals by newer, therapeutically useful chelating agents

H.Vasken Aposhian, Richard M. Maiorino, Diego Gonzalez-Ramirez, Miguel Zuniga-Charles, Zhaofa Xu, Katherine M. Hurlbut, Pablo Junco-Munoz, Richard C. Dart, Mary.M. Aposhian

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 1.32 MB

english, 1995

13

Enzymatic methylation of arsenic compounds. IX. Liver arsenite methyltransferase and arsenate reductase activities in primates

Eric Wildfang, Timothy R Radabaugh, H Vasken Aposhian

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 107 KB

english, 2001

14

Fluorometric determination of 2,3-dimercaptopropane-1-sulfonic acid and other dithiols by precolumn derivatization with bromobimane and column liquid chromatography

Richard M. Maiorino, Gregory L. Weber, H.Vasken Aposhian

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Année:

1986

Langue:

english

Fichier:

PDF, 1.06 MB

english, 1986

15

Evaluation ofDrosophila melanogasteras an alternative animal for studying the neurotoxicity of heavy metals

Jonathan M. Akins, Joyce A. Schroeder, Danny L. Brower, H. Vasken Aposhian

Journal:

Année:

1992

Langue:

english

Fichier:

PDF, 885 KB

english, 1992

16

N-(2,3-Dimercaptopropyl)phthalamidic acid (DMPA) increases polonium-210 excretion

Gregory M. Bogdan, H. Vasken Aposhian

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 442 KB

english, 1990

17

Nature's death

H. Vasken Aposhian

Journal:

Molecular and Cellular Biochemistry

Année:

1973

Langue:

english

Fichier:

PDF, 37 KB

english, 1973

18

Mammalian gene transfer - a poem

H. Vasken Aposhian

Journal:

Molecular and Cellular Biochemistry

Année:

1974

Fichier:

PDF, 26 KB

1974

19

Diversity of inorganic arsenite biotransformation

Sheila M. Healy, Eric Wildfang, Robert A. Zakharyan, H. Vasken Aposhian

Journal:

Biological Trace Element Research

Année:

1999

Langue:

english

Fichier:

PDF, 1.30 MB

english, 1999

20

Urinary excretion of meso-2,3-dimercaptosuccinic acid in human subjects

Aposhian, H Vasken, Maiorino, Richard M, Dart, Richard C, Perry, Dana F

Journal:

Clinical Pharmacology & Therapeutics

Année:

1989

Langue:

english

Fichier:

PDF, 603 KB

english, 1989

21

Protein Expression in the Livers and Urinary Bladders of Hamsters Exposed to Sodium Arsenite

Uttam K. Chowdhury, H. Vasken Aposhian

Journal:

Annals of the New York Academy of Sciences

Année:

2008

Langue:

english

Fichier:

PDF, 375 KB

english, 2008

22

Enzymatic Methylation of Arsenic Compounds: III. The Marmoset and Tamarin, but Not the Rhesus, Monkeys Are Deficient in Methyltransferases That Methylate Inorganic Arsenic

Robert A. Zakharyan, Eric Wildfang, H.Vasken Aposhian

Journal:

Toxicology and Applied Pharmacology

Année:

1996

Langue:

english

Fichier:

PDF, 186 KB

english, 1996

23

Enzymatic Methylation of Arsenic Compounds: V. Arsenite Methyltransferase Activity in Tissues of Mice

Sheila M. Healy, Elizabeth A. Casarez, Felix Ayala-Fierro, H.Vasken Aposhian

Journal:

Toxicology and Applied Pharmacology

Année:

1998

Langue:

english

Fichier:

PDF, 135 KB

english, 1998

24

Enzymatic Methylation of Arsenic Compounds: VI. Characterization of Hamster Liver Arsenite and Methylarsonic Acid Methyltransferase Activitiesin Vitro

Eric Wildfang, Robert A. Zakharyan, H.Vasken Aposhian

Journal:

Toxicology and Applied Pharmacology

Année:

1998

Langue:

english

Fichier:

PDF, 147 KB

english, 1998

25

Arsenite Methylation by Methylvitamin B12and Glutathione Does Not Require an Enzyme

Robert A. Zakharyan, H.Vasken Aposhian

Journal:

Toxicology and Applied Pharmacology

Année:

1999

Langue:

english

Fichier:

PDF, 62 KB

english, 1999

26

Enzymatic Methylation of Arsenic Compounds. VII. Monomethylarsonous Acid (MMAIII) Is the Substrate for MMA Methyltransferase of Rabbit Liver and Human Hepatocytes

Robert A. Zakharyan, Felix Ayala-Fierro, William R. Cullen, Dean M. Carter, H.Vasken Aposhian

Journal:

Toxicology and Applied Pharmacology

Année:

1999

Langue:

english

Fichier:

PDF, 87 KB

english, 1999

27

Monomethylarsonous Acid (MMAIII) Is More Toxic Than Arsenite in Chang Human Hepatocytes

Jay S. Petrick, Felix Ayala-Fierro, William R. Cullen, Dean E. Carter, H. Vasken Aposhian

Journal:

Toxicology and Applied Pharmacology

Année:

2000

Langue:

english

Fichier:

PDF, 81 KB

english, 2000

28

DMPS–Arsenic Challenge Test: II. Modulation of Arsenic Species, Including Monomethylarsonous Acid (MMAIII), Excreted in Human Urine

H.Vasken Aposhian, Baoshan Zheng, Mary M. Aposhian, X.Chris Le, Mariano E. Cebrian, William Cullen, Robert A. Zakharyan, Mingsheng Ma, Richard C. Dart, Zhai Cheng, Paul Andrewes, Luke Yip, Gerald F. O

Journal:

Toxicology and Applied Pharmacology

Année:

2000

Langue:

english

Fichier:

PDF, 158 KB

english, 2000

29

Protection of mice against the lethal effects of sodium arsenite—A quantitative comparison of a number of chelating agents

H.Vasken Aposhian, Charles H. Tadlock, Thomas E. Moon

Journal:

Toxicology and Applied Pharmacology

Année:

1981

Langue:

english

Fichier:

PDF, 623 KB

english, 1981

30

dl- and meso-dimercaptosuccinic acid: In vitro and in vivo studies with sodium arsenite

H.Vasken Aposhian, Chin-An Hsu, Todd D. Hoover

Journal:

Toxicology and Applied Pharmacology

Année:

1983

Langue:

english

Fichier:

PDF, 671 KB

english, 1983

31

N-(2,3-dimercaptopropyl)phthalamidic acid: Protection, in vivo and in vitro, against arsenic intoxication

Eric R. Stine, Chin-An Hsu, Todd D. Hoover, H. Vasken Aposhian, D.E. Carter

Journal:

Toxicology and Applied Pharmacology

Année:

1984

Langue:

english

Fichier:

PDF, 670 KB

english, 1984

32

Dimercaptan metal-binding agents influence the biotransformation of arsenite in the rabbit

Richard M. Maiorino, H.Vasken Aposhian

Journal:

Toxicology and Applied Pharmacology

Année:

1985

Langue:

english

Fichier:

PDF, 992 KB

english, 1985

33

Determination and metabolism of dithiol chelating agents: VIII. Metal complexes of meso-dimercaptosuccinic acid

Mario Rivera, Wei Zheng, H.Vasken Aposhian, Quintus Fernando

Journal:

Toxicology and Applied Pharmacology

Année:

1989

Langue:

english

Fichier:

PDF, 772 KB

english, 1989

34

Determination and metabolism of dithiol chelating agents: VI. Isolation and identification of the mixed disulfides of meso-2,3-Dimercaptosuccinic acid with l-cysteine in human urine

Richard M. Maiorino, David C. Bruce, H.Vasken Aposhian

Journal:

Toxicology and Applied Pharmacology

Année:

1989

Langue:

english

Fichier:

PDF, 954 KB

english, 1989

35

The metabolism of inorganic arsenic oxides, gallium arsenide, and arsine: a toxicochemical review

Dean E Carter, H.Vasken Aposhian, A.Jay Gandolfi

Journal:

Toxicology and Applied Pharmacology

Année:

2003

Langue:

english

Fichier:

PDF, 393 KB

english, 2003

36

Oxidation and detoxification of trivalent arsenic species

H.Vasken Aposhian, Robert A. Zakharyan, Mihaela D. Avram, Michael J. Kopplin, Michael L. Wollenberg

Journal:

Toxicology and Applied Pharmacology

Année:

2003

Langue:

english

Fichier:

PDF, 249 KB

english, 2003

37

Behavioral Effects of Low-Level Exposure to Hg0 Among Dental Professionals: A Cross-Study Evaluation of Psychomotor Effects

Alvah C. Bittner JR., Diana Echeverria, James S. Woods, H.Vasken Aposhian, Conrad Naleway, Michael D. Martin, Roderick K. Mahurin, Nicholas J. Heyer, Margaret Cianciola

Journal:

Neurotoxicology and Teratology

Année:

1998

Langue:

english

Fichier:

PDF, 267 KB

english, 1998

38

PENICILLAMINE AND ANALOGOUS CHELATING AGENTS

H. Vasken Aposhian

Journal:

Annals of the New York Academy of Sciences

Année:

1971

Langue:

english

Fichier:

PDF, 507 KB

english, 1971

39

GENE THERAPY SYSTEMS: THE NEED, EXPERIMENTAL APPROACH, AND IMPLICATIONS

Joseph V. Osterman, Anna Waddell, H. Vasken Aposhian

Journal:

Annals of the New York Academy of Sciences

Année:

1971

Langue:

english

Fichier:

PDF, 314 KB

english, 1971

40

Transport and Control of Manganese Ions in the Central Nervous System

H.Vasken Aposhian, Russell T. Ingersoll, Erwin B. Montgomery Jr.

Journal:

Environmental Research

Année:

1999

Langue:

english

Fichier:

PDF, 59 KB

english, 1999

41

Central Nervous System Toxicity of Manganese: I. Inhibition of Spontaneous Motor Activity in Rats after Intrathecal Administration of Manganese Chloride

Russell T. Ingersoll, Erwin B. Montgomery Jr., H.Vasken Aposhian

Journal:

Fundamental and Applied Toxicology

Année:

1995

Fichier:

PDF, 534 KB

1995

42

Determination and metabolism of dithiol chelating agents: IV. Urinary excretion of meso-2,3-dimercaptosuccinic acid and mercaptosuccinic acid in rabbits given meso-2,3-dimercaptosuccinic acid

Richard M. Maiorino, H.Vasken Aposhian

Journal:

Biochemical Pharmacology

Année:

1989

Langue:

english

Fichier:

PDF, 833 KB

english, 1989

43

The inhibition of Escherichia coli by l-penicillamine and its reversal by isoleucine, valine or leucine

Robert M. Blair, H. Vasken Aposhian

Journal:

Biochimica et Biophysica Acta

Année:

1958

Langue:

english

Fichier:

PDF, 121 KB

english, 1958

44

The reversal of the inhibitory activity of l-penicillamine by branched chain amino acids

H. Vasken Aposhian, Robert M. Blair, Myron Morris, Clarence H. Smithson

Journal:

Biochimica et Biophysica Acta

Année:

1959

Langue:

english

Fichier:

PDF, 460 KB

english, 1959

45

Variability in human metabolism of arsenic

Christopher A. Loffredo, H.Vasken Aposhian, Mariano E. Cebrian, Hiroshi Yamauchi, Ellen K. Silbergeld

Journal:

Environmental Research

Année:

2003

Langue:

english

Fichier:

PDF, 139 KB

english, 2003

46

Pharmacokinetics of meso-2,3- dimercaptosuccinic acid in patients with lead poisoning and in healthy adults

Richard C. Dart, Katherine M. Hurlbut, Richard M. Maiorino, Michael Mayersohn, H.Vasken Aposhian, Leslie V.Boyer Hassen

Journal:

The Journal of Pediatrics

Année:

1994

Langue:

english

Fichier:

PDF, 618 KB

english, 1994

47

Erratum to “Enzymatic methylation of arsenic compounds: IV. In vitro and in vivo deficiency of the methylation of arsenite and monomethylarsonic acid in the guinea pig” [Mutation Res. 386 (1997) 229–239]

Sheila M Healy, Robert A Zakharyan, H Vasken Aposhian

Journal:

Mutation Research/Reviews in Mutation Research

Année:

1997

Langue:

english

Fichier:

PDF, 36 KB

english, 1997

48

Enzymatic methylation of arsenic compounds: IV. In vitro and in vivo deficiency of the methylation of arsenite and monomethylarsonic acid in the guinea pig

Sheila M. Healy, Robert A. Zakharyan, H. Vasken Aposhian

Journal:

Mutation Research/Reviews in Mutation Research

Année:

1997

Langue:

english

Fichier:

PDF, 1.05 MB

english, 1997

49

DMSA, DMPS, and DMPA—as arsenic antidotes

H.Vasken Aposhian, Dean E. Carter, Todd D. Hoover, Chin-An Hsu, Richard M. Maiorino, Eric Stine

Journal:

Fundamental and Applied Toxicology

Année:

1984

Langue:

english

Fichier:

PDF, 1.08 MB

english, 1984

50

Arsenic Toxicology: Five Questions †

Aposhian, H. Vasken, Aposhian, Mary M.

Journal:

Chemical Research in Toxicology

Année:

2006

Langue:

english

Fichier:

PDF, 821 KB

english, 2006